MED64-Quad II

Microelectrode Array Recording System (AlphaMED)


The most sensitive and flexible medium throughput MEA system for both acute and cultured applications

MED64-Quad II system is a medium throughput MEA system both for acute and cultured applications. Extracellular signals are recorded from 4 independent Probes/Connectors, which will give high flexibility. It is a powerful solution for drug discovery screening. The MED64’s high fidelity will provide more accurate and reliable data allowing for advanced screening.


  • Acquire extracellular signals from 4 samples (16 electrodes/sample).
  • Stimulation to all samples sequentially (up to 2 electrodes simultaneously) using internal stimulator.
  • Unrivaled signal-to-noise ratio of 0.8 μV RMS noise level.
  • Large current-driven stimulation via any electrode.
  • High-quality evoked signal without interference of stimulus artifacts.
  • Recording inside of a humidified incubator.
  • One system can be used for multiple experiments with its amplifier’s broad acquisition bandwidth and analog lowpass/highpass filter.
  • Analyze data online during your experiment or offline after.
  • Suitable for acute slices, slice cultures, and cell cultures.
  • Low-cost shift to MED64-Allegro/Basic System.


System Configuration

MED Probe 16   (4)

MED Connector  (4)

MED64 Head Amplifier

MED64 Main Amplifier

Mobius Software

Data acquisition PC



Number of channels / sample

RMS Noise (Typical)
    14 nV/√Hz
    *MED-515A input:
    0.8 μV (f < 3 kHz)
    1.2 μV (f < 5 kHz)
    1.8 μV (f < 10 kHz)

Number of samples

    × 200 - 2170

Acquisition bandwidth
    0.1Hz - 10 kHz

Analog low-cult filter
    0.1, 1, 10, 100 Hz

No. of stimulator channel

Analog high-cut filter
    1.0, 2.0, 2.5, 5.0, 7.5, 10 kHz   

Stimulus output format

Input impedance
    100 MΩ

Max. output current
    ± 200 μA

Output impedance

Signal output
    Resolution    16 bit
    Output format    USB
    Sampling rate    Up to 20 kHz / channel


Also See:

PDF file MED64 Product Brochure
( PDF)