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XenoWorksTM is a modular microinjection system designed to meet a wide variety of
application needs.
SUTTER´s experience with precision motor
control has culminated in this state-of-the-art
system. The
XenoWorksTM Micromanipulator uses a classic inverted joystick design for
excellent ergonomics, intuitively linking the user
with the micropipette.
Combined with our smooth, responsive
stepper-motor drives, the XenoWorksTM
Manipulator provides exceptional mechanical stability,
sensitivity, and range of movement.
The XenoWorksTM Digital Microinjector
was designed for precision manipulation of cells via an easy-to-use
interface. The Digital Microinjector employs a
self-contained vacuum channel for gentle
suspension-cell holding applications. A second channel is available for both high-pressure
injection and gentle positive/negative pressure for
transfer of embryonic stem cells. Both injection
duration and pressure are easily selectable using
rotary knobs on the remote interface.
The internal low-speed compressor removes the
need for an external pressure supply. The XenoWorksTM
family also includes the Analog Microinjector
for simple cell holding and transfer applications,
which incorporates the same smooth response and
ergonomic design of our other XenoWorksTM products.
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TYPICAL APPLICATIONS
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Pronuclear microinjection of DNA into mouse zygote
Embryonic stem cell transfer into blastocysts
Somatic cell nuclear transfer
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Intracytoplasmic sperm injection (ICSI)
Piezo-assisted sperm-mediated transgenesis and
nuclear ransfer
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Contact SPT for suitability of XenoWorks for applications
not
listed here
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SYSTEM FEATURES
XENOWORKS
MICROMANIPULATOR
Height-
and tension-adjustable inverted joystick for optimal ergonomics
Exceptionally
smooth and responsive micropipette movement
Variable
movement range - 6 settings from coarse to ultra-fine
User
definable memory positions, including “Work” and z-axis
lower limit
A
wide 25mm of travel in all three axes
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XENOWORKS DIGITAL
MICROINJECTOR
Independent “hold” and inject/transfer
channels
Up to 5,600 hPa of injection pressure
Remote keypad with rotary controls and high-
visibility
LED displays
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XENOWORKS ANALOG MICROINJECTOR
Highly stabble, drift free
Coaial coarse and fine displacement (10:1 ratio) for fast filling and
precision
control
Use with a variety of
hydraulic fluids,
including oil, air and water
Interchangeable syringes
(500µl standard, 100µl and 1000µl options)
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Specifications
XenoWorks
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XenoWorks
MICROMANIPULATOR INPUT DEVICE
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Height- and resistance-adjustable inverted
joystick with integral declutch, 6 position rotary
range control, low-profile base |
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RANGE SETTINGS (ONE FULL JOYSTICK SWING) |
12mm; 3.3mm; 880µm; 400µm; 200µm; 100µm |
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MICROPIPETTE POSITION MEMORY |
1 user-defined set-point – “Work”;
1 user-defined z-axis limit –
“Floor”; 2
preset points – “Home” and
“Setup” |
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MAXIMUM MOTOR SPEED / TRAVEL RANGE |
5.5mms-1 / 25mm |
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MICROPIPETTE HOLDER GRIP |
4mm outer diameter |
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ELECTRICAL
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115/230 Volts50/60 Hertz |
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XenoWorks
DIGITAL
MICROINJECTOR FUNCTIONS
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Hold,
Inject, Transfer, Clear
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PRESSURE CHANNELS
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1 Hold, 1 Inject/Transfer |
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PRESSURE RANGE
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Hold:
-350 to +350 hPa, 7hPa steps
Inject:
0 – 5,600 hPa, 7hPa steps
Transfer: -175 to
+175 hPa, 7hPa steps |
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INJECTION DURATION |
Variable: 0.01 – 10s in 0.1s increments |
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INJECTION ACTIVATION |
Hand- or foot-switch |
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MICROPIPETTE COMPATIBILITY |
1mm
O.D. capillary glass / other sizes
available upon request |
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ELECTRICAL
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110 or 220 Volts (please specify) 50/60 Hertz |
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XenoWorks
ANALOG MICROINJECTOR |
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COARSE
: FINE RATIO
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10:1
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INTERCHANGEABLE
SYRINGE RESERVOIR
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1000µl, 500µl, 100µl
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DISPLACEMENT / TURN
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500µl syringe – 5.2µl
coarse, 0.5µl fine
1000µl syringe – 10.4µl coarse, 1.04µl fine
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TUBING |
1m
ETFE |
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MICROPIPETTE
HOLDER
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Diameter:
4mm
Accepts:1mm
O.D. capillary glass (other sizes can be upon request)
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ELECTRICAL |
115/230 Volts50/60 Hertz |
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Microinjection
Systems
Products
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