Dagan

For several years the engineers Dagan Corporation have been  making researchers aware of the benefits of using integrating and semi-integrating patch clamps for:

  WHOLE CELL

  SINGLE CHANNEL

  BILAYERS

  HIGH SPEED CURRENT CLAMPING

 UNEQUALLED FEATURES

• New improved noise specifications when using capacitance compensation (Cp) (i.e. virtually no increase in noise), 0.2 pA-RMS 10 kHz bandwidth with Cp off.
• Fast current clamp. All other resistive or integrating patch clamps are about 4 to 30 times slower. The rise time of the current step for a 500 MW /33pF 
  with a 2 MW electrode whole cell model is 4µs (3902 headstage). Compare this to another integrating patch clamp that is as slow as 140gs (about 1.1 kHz bandwidth).
• Automatic polarity control is available with the flick of a switch. Now you have a choice.
• Four values of seal test voltages; others only have one.
• Independent Holding Current dial for current clamp (unique to the 3900).
• Audio monitor (especially useful for bilayers).
• All modes, modifiers of operation, and GAIN are computer controllable.
• Output zeroing.
• Twelve position 80db/decade Bessel filter.
• Rupture (Zap) Generator to aid in cell impalement.
• Automatic holding or search (i.e., track) Junction Potential.

 OPTIONAL EXPANSION

   The optional expander section allows room to grow. The Dagan 3900 is not easily outdated when new features and functions are needed.

• Optional supercharging and Hypercharge (automatic supercharging with blanking of current record).
• Optional Prefilter control allows highest percentage of series resistance compensation of any whole cell patch clamp.
• Optional triangle wave Generator and digital capacitance meter for bilayers.
• Optional step command Generator for bilayers.
• Optional whole cell capacitive transient nulling with readout of membrane capacitance.

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